Anti-GRAP Antibody Picoband® PE Conjugated
Product Specifications
Background
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Synonyms
GRAP; GRB2 related adapter protein; GRB2 related adaptor protein
UNSPSC
41116129
HS Code
3002.1
Gene Name
GRAP
Gene ID
10750
UniProt
Q13588
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human GRAP recombinant protein (Position: D133-L217) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Liquid
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
25 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
GRB2 related adaptor protein
Protein Name
GRB2-related adapter protein
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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