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Anti-DCPS Antibody Picoband® PE Conjugated

Product Specifications

Background

This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.

Synonyms

EC:3.6.1.59; Decapping scavenger enzyme; decapping enzyme; scavenger; DCS-1; DCS1

UNSPSC

41116129

HS Code

3002.1

Gene Name

DCPS

Gene ID

28960

UniProt

Q96C86

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human DCPS recombinant protein (Position: M1-S337) .

Clonality

Polyclonal

Applications

Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Liquid

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

39 kDa

Applications Notes

Optimal dilutions should be determined by end users.

Gene Name Synonym

Decapping enzyme, scavenger

Protein Name

M7GpppX diphosphatase

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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