BE1218
BE1218 is a liver X receptor (LXR) inverse agonist with IC50 values of 9 nM and 7 nM against LXRα and LXRβ, respectively[1].
Product Specifications
CAS Number
2893967-40-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
LXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/be1218.html
Purity
99.86
Solubility
DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=CC(C)=C(C(C)=C1)S(=O)(N(CC2=C(C=CC=C2)F)CC3=CC=C(C=C3)C4=CC(S(C)(=O)=O)=CC=C4)=O
Molecular Formula
C30H30FNO4S2
Molecular Weight
551.69
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Elgendy B, et al. Synthesis and structure activity relationship of the first class of LXR inverse agonists. Bioorg Chem. 2022 Feb;119:105540.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Chicken Inner centromere protein, INCENP ELISA Kit
