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CK1-IN-4

CK1-IN-4 (Compound 59) is an inhibitor for casein kinase CK1δ with IC50 of 2.74 μM. CK1-IN-4 exhibits neuroprotective effect in Ethacrynic acid -treated SH-SY5Y cells[1].

Product Specifications

UNSPSC

12352005

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ck1-in-4.html

Smiles

NC1=NC(NCC2=CC=CC(OC)=C2)=NC3=NC(C4=CC=CS4)=NN31

Molecular Formula

C16H15N7OS

Molecular Weight

353.40

References & Citations

[1]Grieco I, et al., 7-Amino-[1,2,4]triazolo[1,5-a][1,3,5]triazines as CK1δ inhibitors: Exploring substitutions at the 2 and 5-positions. Bioorg Chem. 2024 Jul 17;151:107659.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CK1

Frequently Asked Questions

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