Salvigenin

Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis[1][2].

Product Specifications

CAS Number

[19103-54-9]

Product Name Alternative

Psathyrotin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; ROS Kinase

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/salvigenin.html

Purity

99.93

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=C(OC)C(O)=C13

Molecular Formula

C18H16O6

Molecular Weight

328.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Rafatian G, et al. Increase of autophagy and attenuation of apoptosis by Salvigenin promote survival of SH-SY5Y cells following treatment with H₂O₂. Mol Cell Biochem. 2012 Dec;371 (1-2) :9-22.|[2]Noori S, et al. Antitumor and immunomodulatory effects of salvigenin on tumor bearing mice. Cell Immunol. 2013 Nov-Dec;286 (1-2) :16-21.