Anti-AMBRA1 Antibody Picoband® APC Conjugated
Product Specifications
Background
Enables enzyme binding activity; protein phosphatase activator activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including macroautophagy; positive regulation of free ubiquitin chain polymerization; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in cytosol. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in cytoskeleton; mitochondrion; and nucleus. Biomarker of multiple system atrophy.
Synonyms
AMBRA1; KIAA1736; Activating molecule in BECN1-regulated autophagy protein 1
UNSPSC
41116129
HS Code
3002.1
Gene Name
AMBRA1
Gene ID
55626
UniProt
Q9C0C7
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human AMBRA1 recombinant protein (Position: R21-R1093) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
142 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Autophagy and beclin 1 regulator 1
Protein Name
Activating molecule in BECN1-regulated autophagy protein 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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