Anti-SIP1/GEMIN2 Antibody Picoband® FITC Conjugated
Product Specifications
Background
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Synonyms
GEMIN2; SIP1; Gem-associated protein 2; Gemin-2; Component of gems 2; Survival of motor neuron protein-interacting protein 1; SMN-interacting protein 1
UNSPSC
41116129
HS Code
3002.1
Gene Name
GEMIN2
Gene ID
8487
UniProt
O14893
Host
Rabbit
Reactivity
Human, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SIP1/GEMIN2 recombinant protein (Position: E32-D140) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
32 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Gem nuclear organelle associated protein 2
Protein Name
Gem-associated protein 2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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