Pimelic Diphenylamide 106 (analog)

Pimelic Diphenylamide 106 analog is the analog of Pimelic Diphenylamide 106, with unknown activity.

Product Specifications

CAS Number

[2070015-24-4]

Product Name Alternative

RGFA-8 analog; TC-H 106 analog

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Pimelic-Diphenylamide-106-analog.html

Purity

96.06

Solubility

DMSO : ≥ 30 mg/mL

Smiles

O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=C(C)C=C2)=O

Molecular Formula

C21H27N3O2

Molecular Weight

353.46

References & Citations

[1]Chou CJ, et al. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem. 2008 Dec 19;283 (51) :35402-35409.|[2]Xu C, et al. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol. 2009 Sep 25;16 (9) :980-989.