Anti-GBA/GBA1 Antibody Picoband® Fluoro647 Conjugated
Selected Variant
A01162-2-Fluoro647
Size: 100 µg/Vial
Product Specifications
Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Synonyms
GBA; GC; GLUC; Lysosomal acid glucosylceramidase; Lysosomal acid GCase; EC 3.2.1.45; Acid beta-glucosidase; Alglucerase; Beta-glucocerebrosidase; Beta-GC; Cholesterol glucosyltransferase; SGTase; EC 2.4.1.-; Cholesteryl-beta-glucosidase; EC 3.2.1.104; D-glucosyl-N-acylsphingosine glucohydrolase; Imiglucerase
UNSPSC
41116129
HS Code
3002.1
Gene Name
GBA1
Gene ID
2629
UniProt
P04062
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human GBA/GBA1 recombinant protein (Position: N58-Q208) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
60 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Glucosylceramidase beta 1
Protein Name
Lysosomal acid glucosylceramidase
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Price
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