DL-Dithiothreitol (DTT, High Purity)

<strong>DL-Dithiothreitol (DTT, High Purity)</strong>_x000D_ <strong>Catalog number:</strong> B2010240_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 1 g_x000D_ <strong>pH:</strong> na_x000D_ <strong>Supplied as:</strong> Ready-to-use_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> high purity reducing agent (&gt; 99% by titration) also known as Cleland’s reagent._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> threo-1,4-Dimercapto-2,3-butanediol, Cleland’s reagent, DTT_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered on a 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bub CB. Dithiothreitol treatment of red blood cells. Immunohematology. 2017_x000D_ Dec;33(4):170-172._x000D_ _x000D_ 2: Lorenzen H, Lone Akhtar N, Nielsen M, Svendsen L, Andersen P. Thirty-three-_x000D_ day storage of dithiothreitol-treated red blood cells used to eliminate_x000D_ daratumumab interference in serological testing. Vox Sang. 2018_x000D_ Oct;113(7):686-693._x000D_ _x000D_ 3: Liang P, Canoura J, Yu H, Alkhamis O, Xiao Y. Dithiothreitol-Regulated_x000D_ Coverage of Oligonucleotide-Modified Gold Nanoparticles To Achieve Optimized_x000D_ Biosensor Performance. ACS Appl Mater Interfaces. 2018 Jan 31;10(4):4233-4242._x000D_ _x000D_ 4: Han JC, Han GY. A procedure for quantitative determination of_x000D_ tris(2-carboxyethyl)phosphine, an odorless reducing agent more stable and_x000D_ effective than dithiothreitol. Anal Biochem. 1994 Jul;220(1):5-10._x000D_ _x000D_ 5: Lin M, Yu JZ. Dithiothreitol (DTT) concentration effect and its implications_x000D_ on the applicability of DTT assay to evaluate the oxidative potential of_x000D_ atmospheric aerosol samples. Environ Pollut. 2019 Aug;251:938-944._x000D_ _x000D_ 6: Heidari R, Ghanbarinejad V, Mohammadi H, Ahmadi A, Esfandiari A, Azarpira N,_x000D_ Niknahad H. Dithiothreitol supplementation mitigates hepatic and renal injury in_x000D_ bile duct ligated mice: Potential application in the treatment of cholestasis-_x000D_ associated complications. Biomed Pharmacother. 2018 Mar;99:1022-1032._x000D_ _x000D_ 7: Lopes de Almeida JP, Saldanha C. Dithiothreitol revisited in red cells: a new_x000D_ head for an old hat. Clin Hemorheol Microcirc. 2010;46(1):51-6. d_x000D_ _x000D_ 8: Zhang N, Dong B, Kong X, Wang C, Song W, Lin W. Two-photon imaging of_x000D_ 1,4-dithiothreitol (DTT) by a red-emissive fluorescent probe in living cells,_x000D_ tissues and animals. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Dec_x000D_ 5;205:528-533._x000D_ _x000D_ 9: Wang J, Lin X, Lu L, Wu Y, Zhang H, Lv Q, Liu W, Zhang Y, Zhuang S. Temporal_x000D_ variation of oxidative potential of water soluble components of ambient_x000D_ PM_2.5 measured by dithiothreitol (DTT) assay. Sci Total Environ. 2019_x000D_ Feb 1;649:969-978._x000D_ _x000D_ 10: Kara DA, Borzova VA, Markossian KA, Kleymenov SY, Kurganov BI. A change in_x000D_ the pathway of dithiothreitol-induced aggregation of bovine serum albumin in the_x000D_ presence of polyamines and arginine. Int J Biol Macromol. 2017 Nov;104(Pt_x000D_ A):889-899._x000D_ _x000D_ 11: Yu H, Wei J, Cheng Y, Subedi K, Verma V. Synergistic and Antagonistic_x000D_ Interactions among the Particulate Matter Components in Generating Reactive_x000D_ Oxygen Species Based on the Dithiothreitol Assay. Environ Sci Technol. 2018 Feb_x000D_ 20;52(4):2261-2270._x000D_ _x000D_ 12: Youssef M, Arnesen C, Arledge C, Langley C, Sylvester D, Sikora J, Marques_x000D_ MB, Long Zheng X, Williams LA 3rd. Validation and cost-effectiveness of an in-_x000D_ house DL-dithiothreitol (DTT) treatment protocol for daratumumab patients in a_x000D_ large tertiary care hospital provides gateway for implementation in smaller_x000D_ community hospitals. <a href="https://pubmed.ncbi.nlm.nih.gov/30639177/">Transfus Apher Sci.</a> 2019 Apr;58(2):152-155. d_x000D_ _x000D_ <strong>Products Related to DL-Dithiothreitol (DTT, High Purity)</strong><a>: Biochemical Buffers and Solutions</a>