Anti-HHIP Antibody Picoband® FITC Conjugated
Product Specifications
Background
This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD) . A single nucleotide polymorphism in this gene is also strongly associated with human height.
Synonyms
HHIP; HIP; UNQ5825/PRO19644; Hedgehog-interacting protein; HHIP; HIP
UNSPSC
41116129
HS Code
3002.1
Gene Name
HHIP
Gene ID
64399
UniProt
Q96QV1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human HHIP recombinant protein (Position: N99-M688) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
79 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Hedgehog interacting protein
Protein Name
Hedgehog-interacting protein
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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