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Anti-HHIP Antibody Picoband® FITC Conjugated

Product Specifications

Background

This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD) . A single nucleotide polymorphism in this gene is also strongly associated with human height.

Synonyms

HHIP; HIP; UNQ5825/PRO19644; Hedgehog-interacting protein; HHIP; HIP

UNSPSC

41116129

HS Code

3002.1

Gene Name

HHIP

Gene ID

64399

UniProt

Q96QV1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human HHIP recombinant protein (Position: N99-M688) .

Clonality

Polyclonal

Applications

Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

79 kDa

Applications Notes

Optimal dilutions should be determined by end users.

Gene Name Synonym

Hedgehog interacting protein

Protein Name

Hedgehog-interacting protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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