Anti-CD151 Antibody Picoband® PE Conjugated

CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

E.coli-derived human CD151 recombinant protein (Position: A113-A175) . Human CD151 shares 88.7% amino acid (aa) sequence identity with both mouse and rat CD151.

Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.