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Echinatin (Standard)

Echinatin (Standard) is the analytical standard of Echinatin. This product is intended for research and analytical applications. Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2].

Product Specifications

CAS Number

34221-41-5

UNSPSC

12352005

Target

Apoptosis; Autophagy; NOD-like Receptor (NLR) ; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation; Others

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/echinatin-standard.html

Smiles

O=C(C1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2OC

Molecular Formula

C16H14O4

Molecular Weight

270.28

References & Citations

[1]Liang M, et al. Antioxidant Mechanisms of Echinatin and Licochalcone A. Molecules. 2018 Dec 20;24 (1) .|[2]Xu G, et al. Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90. JCI Insight. 2021 Jan 25;6 (2) :e134601.|[3]Niu J, et al. Cardioprotective Effect of Echinatin Against Ischemia/Reperfusion Injury: Involvement of Hippo/Yes-Associated Protein Signaling. Front Pharmacol. 2021 Jan 11;11:593225.|[4]Hong P, et al. Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis. Cell Death Dis. 2020 Jul 13;11 (7) :524.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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