Cephapirin (hemibenzathine)

Cephapirin hemibenzathine is an intrauterine-administered, long-acting cephalosporin antibiotic suitable for the anaerobic environment of the postpartum uterus. Cephapirin hemibenzathine effectively improves the recovery of postpartum buffaloes with subclinical endometritis (SCE) and enhances their reproductive performance. Cephapirin hemibenzathine can be used for the study of subclinical endometritis in postpartum buffaloes[1][2].

Product Specifications

CAS Number

[97468-37-6]

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cephapirin-benzathine.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(CSC3=CC=NC=C3)=O)C1=O)O.C4(CNCCNCC5=CC=CC=C5)=CC=CC=C4.[1/2]

Molecular Formula

C17H17N3O6S2·1/2C16H20N2

Molecular Weight

543.71

Precautions

H317, H334

References & Citations

[1]Nehru DA, et al. Clinical efficacy of intrauterine cephapirin benzathine administration on clearance of uterine bacteria and subclinical endometritis in postpartum buffaloes. Reprod Domest Anim. 2019 Feb;54 (2) :317-324. |[2]Kasimanickam R, et al. The effect of a single administration of cephapirin or cloprostenol on the reproductive performance of dairy cows with subclinical endometritis. Theriogenology. 2005 Feb;63 (3) :818-30.