Anti-TrkB/NTRK2 Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Synonyms
NTRK2; TRKB; BDNF/NT-3 growth factors receptor; EC 2.7.10.1; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
UNSPSC
41116129
HS Code
3002.1
Gene Name
NTRK2
Gene ID
4915
UniProt
Q16620
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TrkB/NTRK2 recombinant protein (Position: N148-G822) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Liquid
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
92 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Neurotrophic receptor tyrosine kinase 2
Protein Name
BDNF/NT-3 growth factors receptor
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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