WIZ degrader 4
WIZ degrader 4 (Example 1) is a WIZ degrader with an AC50 value of 160 nM. WIZ degrader 4 can be used to investigate sickle cell disease (SCD) and thalassemia[1].
Product Specifications
CAS Number
2879250-22-1
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/wiz-degrader-4.html
Purity
99.37
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCN1CCC[C@H](C1)OC2=CC=C3C(N(CC3=C2)C4CCC(NC4=O)=O)=O
Molecular Formula
C20H25N3O4
Molecular Weight
371.43
References & Citations
[1]Simone BONAZZI, et al. 3- (1-oxoisoindolin-2-yl) piperidine-2,6-dione derivatives and medical uses thereof. WO2022254362A1.2022-12-08.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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