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WIZ degrader 4

WIZ degrader 4 (Example 1) is a WIZ degrader with an AC50 value of 160 nM. WIZ degrader 4 can be used to investigate sickle cell disease (SCD) and thalassemia[1].

Product Specifications

CAS Number

2879250-22-1

UNSPSC

12352005

Target

Histone Acetyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/wiz-degrader-4.html

Purity

99.37

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCN1CCC[C@H](C1)OC2=CC=C3C(N(CC3=C2)C4CCC(NC4=O)=O)=O

Molecular Formula

C20H25N3O4

Molecular Weight

371.43

References & Citations

[1]Simone BONAZZI, et al. 3- (1-oxoisoindolin-2-yl) piperidine-2,6-dione derivatives and medical uses thereof. WO2022254362A1.2022-12-08.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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