Dazoxiben (hydrochloride)

Dazoxiben hydrochloride is a potent and orally active thromboxane (TX) synthase inhibitor[1].

Product Specifications

CAS Number

[74226-22-5]

Product Name Alternative

UK 37248

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dazoxiben-hydrochloride.html

Purity

99.90

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

OC(C1=CC=C(OCCN2C=CN=C2)C=C1)=O.[H]Cl

Molecular Formula

C12H13ClN2O3

Molecular Weight

268.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Patrignani P, et al. Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism.J Pharmacol Exp Ther. 1984 Feb;228 (2) :472-7.|[2]Yu SM, et al. Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.Br J Pharmacol. 1994 Mar;111 (3) :906-12.