Dazoxiben (hydrochloride)
Dazoxiben hydrochloride is a potent and orally active thromboxane (TX) synthase inhibitor[1].
Product Specifications
CAS Number
74226-22-5
Product Name Alternative
UK 37248
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dazoxiben-hydrochloride.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
OC(C1=CC=C(OCCN2C=CN=C2)C=C1)=O.[H]Cl
Molecular Formula
C12H13ClN2O3
Molecular Weight
268.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Patrignani P, et al. Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism.J Pharmacol Exp Ther. 1984 Feb;228 (2) :472-7.|[2]Yu SM, et al. Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.Br J Pharmacol. 1994 Mar;111 (3) :906-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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