Plozasiran

Plozasiran is an siRNA targeting APOC3 for the study of mixed hyperlipidemia.

Product Specifications

CAS Number

[2379776-40-4]

Product Name Alternative

ARO-APOC3

UNSPSC

12352208

Target

Apolipoprotein

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/plozasiran.html

Purity

96.87

Smiles

[Plozasiran]

Molecular Formula

C493H654F11N164O311P43S7

Molecular Weight

15618.77

References & Citations

[1]Gaudet D, Pall D, Watts GF, et al. Plozasiran (ARO-APOC3) for Severe Hypertriglyceridemia: The SHASTA-2 Randomized Clinical Trial. JAMA Cardiol. 2024;9 (7) :620-630.|[2]Gaudet D, Clifton P, Sullivan D, et al. RNA Interference Therapy Targeting Apolipoprotein C-III in Hypertriglyceridemia. NEJM Evid. 2023;2 (12) :EVIDoa2200325.