Anti-Spartan/SPRTN Antibody Picoband® APC Conjugated
Product Specifications
Background
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS) . Alternatively spliced transcript variants have been identified.
Synonyms
C1orf124; DVC1; SPRTN; PRO4323; DDDL1880
UNSPSC
41116129
HS Code
3002.1
Gene Name
SPRTN
Gene ID
83932
UniProt
Q9H040
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human Spartan/SPRTN recombinant protein (Position: D23-R344) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Liquid
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
55 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
SprT-like N-terminal domain
Protein Name
DNA-dependent metalloprotease SPRTN
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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