Coppersensor 1

Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu+ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper (I) ions (Cu+) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases[1].

Product Specifications

CAS Number

[874748-20-6]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/coppersensor-1.html

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

[F-][B+3]1([N]2=C(C)C(CC)=C(C)C2=C(CN(CCSCCSCC)CCSCCSCC)C3=C(C)C(CC)=C(C)[N-]31)[F-]

Molecular Formula

C30H50BF2N3S4

Molecular Weight

629.81

References & Citations

[1]Evan W Miller, et al. Preparation and use of Coppersensor-1, a synthetic fluorophore for live-cell copper imaging. Nat Protoc. 2006;1 (2) :824-7.|[2]Li Zeng, et al. A selective turn-on fluorescent sensor for imaging copper in living cells. J Am Chem Soc. 2006 Jan 11;128 (1) :10-1.