BPH-715
BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1].
Product Specifications
CAS Number
[1059677-23-4]
Product Name Alternative
Tyrosine kinase-IN-1
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/BPH-715.html
Purity
99.62
Solubility
0.5 M NaOH : 80 mg/mL (ultrasonic; adjust pH to 11 with NaOH) |DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCCCCOC1=C[N+](CC(P(O)(O)=O)P(O)([O-])=O)=CC=C1
Molecular Formula
C17H31NO7P2
Molecular Weight
423.38
References & Citations
[1]Singh AP, et al. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul;54 (7) :2987-93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Available Sizes
Curated Selection
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