Desisobutyryl-ciclesonide

Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide. Desisobutyryl-ciclesonide has affinity for the glucocorticoid receptor.

Product Specifications

CAS Number

[161115-59-9]

Product Name Alternative

CIC-AP; Ciclesonide active principle

UNSPSC

12352005

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Desisobutyryl-ciclesonide.html

Purity

99.77

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@@]3(C(CO)=O)[C@@](O[C@H](O3)C4CCCCC4)([H])C[C@@]1([H])[C@]5([H])CCC6=CC(C=C[C@]6(C)[C@@]5([H])[C@@H](O)C2)=O

Molecular Formula

C28H38O6

Molecular Weight

470.60

References & Citations

[1]Silvestri M, et al. Ciclesonide modulates in vitro allergen-driven activation of blood mononuclear cells and allergen-specific T-cell blasts. Immunol Lett. 2012 Jan 30;141 (2) :190-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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