Anti-DNAI1 Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.
Synonyms
PCD; ICS1; Dynein axonemal intermediate chain 1; CILD1
UNSPSC
41116129
HS Code
3002.1
Gene Name
DNAI1
Gene ID
27019
UniProt
Q9UI46
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human DNAI1 recombinant protein (Position: P78-D649) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Liquid
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
79 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Dynein axonemal intermediate chain 1
Protein Name
Dynein axonemal intermediate chain 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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