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Bromo-PEG5-azide

Product Specifications

UNSPSC Description

Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bromo-peg5-azide.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

BrCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Molecular Weight

370.24

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140822/Bromo-PEG5-azide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140822/Bromo-PEG5-azide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1402411-90-8

Available Sizes

Curated Selection

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