MCA
MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[1][2].
Product Specifications
CAS Number
62935-72-2
Product Name Alternative
7-Methoxycoumarin-4-acetic acid
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mca.html
Purity
99.62
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1OC(C=C(OC)C=C2)=C2C(CC(O)=O)=C1
Molecular Formula
C12H10O5
Molecular Weight
234.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Perera NC, et, al. NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. J Immunol. 2013 Sep 1;191 (5) :2700-7.|[2]Choi YH, et, al. Effect of functional groups on the solubilities of coumarin derivatives in supercritical carbon dioxide. Chromatographia. 1998 Jan;47 (93-7) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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