MCA

MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[1][2].

Product Specifications

CAS Number

[62935-72-2]

Product Name Alternative

7-Methoxycoumarin-4-acetic acid

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mca.html

Purity

99.62

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1OC(C=C(OC)C=C2)=C2C(CC(O)=O)=C1

Molecular Formula

C12H10O5

Molecular Weight

234.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Perera NC, et, al. NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. J Immunol. 2013 Sep 1;191 (5) :2700-7.|[2]Choi YH, et, al. Effect of functional groups on the solubilities of coumarin derivatives in supercritical carbon dioxide. Chromatographia. 1998 Jan;47 (93-7) .