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Anti-Adrenomedullin Antibody

Our mouse Adrenomedullin monoclonal antibody from Antibodies Incorporated is produced in-house from clone 1. It detects human Adrenomedullin and is Protein A or Protein G purified. Works in ELISA, WB.

Product Specifications

Background

Human adrenomedullin is a 52 amino acid peptide (MW 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP) . In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance.

Synonyms

ADM, AM, PAMP, pro-adrenomedullin, preproadrenomedullin, proadrenomedullin N-20 terminal peptide

Gene Name

ADM

NCBI Gene ID

133

UniProt

P35318

Host

Mouse

Reactivity

Human

Immunogen

Synthetic human adrenomedullin 1-52

Target

Adrenomedullin

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

1

Type

Primary Antibodies

Applications

ELISA, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

21 kDa (preproadrenomedullin), 6 kDa (mature peptide)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

ABS 027-01 binds human adrenomedullin and shows no cross-reaction with CGRP. The epitope of ABS 027-01 lies within residues 22-52.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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