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Anti-Alpha-Calcitonin Gene-Related Peptide (alpha-CGRP) Antibody

Our mouse Alpha-Calcitonin Gene-Related Peptide (Alpha-CGRP) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 4. It detects human and rat Alpha-Calcitonin Gene-Related Peptide (Alpha-CGRP) and is Protein A or Protein G purified. Works in ELISA, IHC.

Product Specifications

Background

Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects.

Synonyms

CALCA, CALC1, CGRP, CGRP-I, CGRP-alpha, CGRP1, CT, KC, PCT, calcitonin, calcitonin gene-related peptide 1, alpha-type CGRP, calcitonin 1, calcitonin gene-related peptide I, calcitonin/calcitonin-related polypeptide, alpha, katacalcin

Gene Name

CALCA

NCBI Gene ID

796

UniProt

P06881

Host

Mouse

Reactivity

Human and Rat

Immunogen

Synthetic human α-CGRP

Target

Alpha-Calcitonin Gene-Related Peptide (Alpha-CGRP)

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

4

Type

Primary Antibodies

Applications

ELISA, IHC

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

11 kDa (pro-CGRP), 5 kDa (active)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

IHC Dilution

0.1111111111111111

Specificity

ABS 026-04 binds human α-CGRP. Based on inhibition ELISA, ABS 026-04 cross-reacts up to 12% with human β-CGRP and human amylin, while there is little (<4%) cross-reaction with rat α-CGRP. The epitope lies within residues 19-37 of human α-CGRP.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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