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Anti-Vasoactive Intestinal Peptide Antibody

Our mouse Vasoactive Intestinal Peptide monoclonal antibody from Antibodies Incorporated is produced in-house from clone 2. It detects bovine, human, pig, and rat Vasoactive Intestinal Peptide and is Protein A or Protein G purified. Works in ELISA, IF, IHC, WB.

Product Specifications

Background

Vasoactive intestinal peptide (VIP) is a 28 amino acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in humans, cows, pigs and rats. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in humans or peptide histidine-serine (PHI) in pigs or rats, present in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) .

Synonyms

VIP, PHM27, VIP peptides, prepro-VIP

Gene Name

VIP

NCBI Gene ID

7432

UniProt

P01282

Host

Mouse

Reactivity

Bovine, Human, Pig, and Rat

Immunogen

Vasoactive intestinal peptide

Target

Vasoactive Intestinal Peptide

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

2

Type

Primary Antibodies

Applications

ELISA, IF, IHC, WB

Concentration

1 mg/mL ±15%

Dilution

0.7361111111111112

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

16 kDa (recombinant/precursor), 4 kDa (native/active)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

IHC Dilution

0.1111111111111111

Specificity

ABS 023-02 binds to human, bovine, porcine or rat VIP, but does not bind to PHM or PACAP.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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