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Anti-Gelsolin Antibody

Our mouse Gelsolin monoclonal antibody from Antibodies Incorporated is produced in-house from clone 20. It detects human Gelsolin and is Protein A or Protein G purified. Works in ELISA, IF, IHC, WB.

Product Specifications

Background

Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions.

Synonyms

GSN, ADF, AGEL, AMYLD4, gelsolin, actin-depolymerizing factor, brevin, epididymis secretory sperm binding protein

Gene Name

GSN

NCBI Gene ID

2934

UniProt

P06396

Host

Mouse

Reactivity

Human

Immunogen

Gelsolin purified from human plasma

Target

Gelsolin

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

20

Type

Primary Antibodies

Applications

ELISA, IF, IHC, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

83 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

IHC Dilution

4.208333333333333

Specificity

ABS 017-20 binds human gelsolin.

ICC Dilution

1.4305555555555556

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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