Anti-Cdk7/CAK Antibody (Monoclonal, 35C69)

CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7 (CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.

CAK; CDKN7; MO15; CAK1; STK1; p39 Mo15; KINASE SUBUNIT OF CAK; SERINE/THREONINE PROTEIN KINASE 1; CELL DIVISION PROTEIN KINASE 7; 39 kDa protein kinase; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit

Store at -20 ̊C for one year from date of receipt. After reconstitution, at 4 ̊C for one month. It can also be aliquotted and stored frozen at -20 ̊C for six months. Avoid repeated freeze-thaw cycles.