Anti-CDK4 Antibody (Monoclonal, 35C67)

Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.

Store at -20 ̊C for one year from date of receipt. After reconstitution, at 4 ̊C for one month. It can also be aliquotted and stored frozen at -20 ̊C for six months. Avoid repeated freeze-thaw cycles.