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Anti-HLA-DPA1 Antibody Picoband® APC Conjugated

Selected Variant

A02225-1-APC

Size: 100 µg/Vial

Product Specifications

Background

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages) . The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Synonyms

DP (W3) ; DP (W4) ; HLA DP1A; HLA DPA1; HLA SB alpha chain; HLADP; HLADPA1; HLA-DPA1; HLASB; MHC class II DP3 alpha; MHC class II DPA1

UNSPSC

41116129

HS Code

3002.1

Gene Name

HLA-DPA1

Gene ID

3113

UniProt

P20036

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human HLA-DPA1 recombinant protein (Position: G30-H198) .

Clonality

Polyclonal

Applications

Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Liquid

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

29 kDa

Applications Notes

Optimal dilutions should be determined by end users.

Gene Name Synonym

Major histocompatibility complex, class II, DP alpha 1

Protein Name

HLA class II histocompatibility antigen, DP alpha 1 chain

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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