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IDO-IN-7

IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.

Product Specifications

CAS Number

1402836-58-1

Product Name Alternative

NLG-919 analogue; GDC-0919 analogue

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/NLG919.html

Purity

99.80

Solubility

DMSO : 50 mg/mL (ultrasonic) |Ethanol : 25 mg/mL (ultrasonic)

Smiles

OC(C1CCCCC1)CC(C2=C3C=CC=C2)N4C3=CN=C4

Molecular Formula

C18H22N2O

Molecular Weight

282.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Coletti A, et al. Fragment-based approach to identify IDO1 inhibitor building blocks. Eur J Med Chem. 2017 Dec 1;141:169-177.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

IDO1

Available Sizes

Frequently Asked Questions

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