IDO-IN-7
IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.
Product Specifications
CAS Number
[1402836-58-1]
Product Name Alternative
NLG-919 analogue; GDC-0919 analogue
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NLG919.html
Purity
99.80
Solubility
DMSO : 50 mg/mL (ultrasonic) |Ethanol : 25 mg/mL (ultrasonic)
Smiles
OC(C1CCCCC1)CC(C2=C3C=CC=C2)N4C3=CN=C4
Molecular Formula
C18H22N2O
Molecular Weight
282.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Coletti A, et al. Fragment-based approach to identify IDO1 inhibitor building blocks. Eur J Med Chem. 2017 Dec 1;141:169-177.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
IDO1
Available Sizes
Curated Selection
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