Anti-ESX1 Antibody Picoband® HRP Conjugated

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.

ESX1; ESX1L; ESX1R; Homeobox protein ESX1; Extraembryonic, spermatogenesis, homeobox 1 [Cleaved into: Homeobox protein ESX1-N; Homeobox protein ESX1-C]