Anti-GCAT Antibody Picoband® APC Conjugated
Product Specifications
Background
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.
Synonyms
GCAT; KBL; 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; EC 2.3.1.29; Aminoacetone synthase; Glycine acetyltransferase
UNSPSC
41116129
HS Code
3002.1
Gene Name
GCAT
Gene ID
23464
UniProt
O75600
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human GCAT recombinant protein (Position: K45-E410) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
45 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
Glycine C-acetyltransferase
Protein Name
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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