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Anti-FBXL18 Antibody Picoband® APC Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.

Synonyms

FBXL18; FBL18; F-box/LRR-repeat protein 18; F-box and leucine-rich repeat protein 18

UNSPSC

41116129

HS Code

3002.1

Gene Name

FBXL18

Gene ID

80028

UniProt

Q96ME1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human FBXL18 recombinant protein (Position: D13-E794) .

Clonality

Polyclonal

Applications

Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Liquid

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

79 kDa

Applications Notes

Optimal dilutions should be determined by end users.

Gene Name Synonym

F-box and leucine rich repeat protein 18

Protein Name

F-box/LRR-repeat protein 18

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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