Chitin, from crab carapace (powder), biomedical research grade

Chitin, from crab carapace is a long-chain polymer of N-acetylglucosamine with β- (1-4) linkages. Chitin, from crab carapace is found in the exoskeleton of crabs. Chitin, from crab carapace inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from crab carapace exerts antifungal and anti-inflammatory effects. Chitin, from crab carapace can be used in the research of gastric ulcer and candidiasis[1][2].

Product Specifications

CAS Number

[1398-61-4]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Endogenous Metabolite; Fungal; NF-κB

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/chitin.html

Solubility

10 mM in DMSO

Smiles

[Chitin,fromcrabcarapace(powder),biomedicalresearchgrade]

Precautions

H302, H315, H319, H335

References & Citations

[1]Bernabé P, et al. Chilean crab (Aegla cholchol) as a new source of chitin and chitosan with antifungal properties against Candida spp. Int J Biol Macromol. 2020 Apr 15;149:962-975. |[2]Amelia R, et al. Chitin Extracted from the Shell of Blue Swimming Crabs (Portunus pelagicus Linn.) Inhibits NF-kappaB p65 in Ethanol-Induced Gastric Ulcerative Wistar Rats. Mar Drugs. 2023 Sep 12;21 (9) :488.