9-Amino-6-chloro-2-methoxyacridine

9-Amino-6-chloro-2-methoxyacridine (ACMA) is a pH-sensitive fluorescent dye widely used to monitor vacuolar and lysosomal pH dynamics. It is a vital tool for studying proton-coupled transport mechanisms, such as H+/solute antiporters, in both in vitro assays and in vivo cellular imaging experiments.