Cadisegliatin
Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes[1][2].
Product Specifications
CAS Number
859525-02-3
Product Name Alternative
TTP-399
UNSPSC
12352005
Target
Glucokinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cadisegliatin.html
Purity
99.80
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(CSC1=CN=C(S1)NC(N(C2CCCCC2)[C@H]3CC[C@@H](CC3)OCCC)=O)=O
Molecular Formula
C21H33N3O4S2
Molecular Weight
455.63
References & Citations
[1]International Nonproprietary Names for Pharmaceutical Substances (INN) |[2]Adrian Vella, et al. Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator. Sci Transl Med. 2019 Jan 16;11 (475) :eaau3441.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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