Cadisegliatin

Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes[1][2].

Product Specifications

CAS Number

[859525-02-3]

Product Name Alternative

TTP-399

UNSPSC

12352005

Target

Glucokinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cadisegliatin.html

Purity

99.80

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC(CSC1=CN=C(S1)NC(N(C2CCCCC2)[C@H]3CC[C@@H](CC3)OCCC)=O)=O

Molecular Formula

C21H33N3O4S2

Molecular Weight

455.63

References & Citations

[1]International Nonproprietary Names for Pharmaceutical Substances (INN) |[2]Adrian Vella, et al. Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator. Sci Transl Med. 2019 Jan 16;11 (475) :eaau3441.