Imazalil (Standard)

Imazalil (Standard) is the analytical standard of Imazalil. This product is intended for research and analytical applications. Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder[1][2][3].

Product Specifications

CAS Number

[35554-44-0]

Product Name Alternative

Enilconazole (Standard)

UNSPSC

12352005

Target

Fungal; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/imazalil-standard.html

Smiles

C=CCOC(C1=CC=C(Cl)C=C1Cl)CN2C=CN=C2

Molecular Formula

C14H14Cl2N2O

Molecular Weight

297.18

References & Citations

[1]Hiroyuki Kojima, et al. Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ. Toxicol Appl Pharmacol. 2012 Mar 15;259 (3) :338-45.|[2]Shohei Yoshimaru, et al. Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR. J Toxicol Sci. 2018;43 (7) :443-450.|[3]Cuiyuan Jin, et al. Chronic exposure of mice to low doses of imazalil induces hepatotoxicity at the physiological, biochemical, and transcriptomic levels. Environ Toxicol. 2018 Jun;33 (6) :650-658.