Hydroxy-PP-Me
Hydroxy-PP-Me is a selective CBR1 inhibitor with an IC50 of 759 nM. Hydroxy-PP-Me can inhibit serum starvation-induced apoptosis. Hydroxy-PP-Me can enhance the cytotoxic effects of Daunorubicin and As2O3 on tumor cells. Hydroxy-PP-Me can be used in the research of cancer such as leukemia[1][2].
Product Specifications
CAS Number
833481-77-9
UNSPSC
12352005
Target
Apoptosis; NADPH Oxidase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hydroxy-pp-me.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=CC(C2=CN(C(C)C)C3=C2C(NC)=NC=N3)=C1
Molecular Formula
C16H18N4O
Molecular Weight
282.34
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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