Physalaemin
Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with high affinity.
Product Specifications
CAS Number
2507-24-6
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Physalaemin.html
Solubility
10 mM in H2O
Smiles
OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCCCN)NC([C@H](CC(N)=O)NC([C@H]3N(CCC3)C([C@H](CC(O)=O)NC([C@H](C)NC([C@H]4NC(CC4)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C58H84N14O16S
Molecular Weight
1265.44
References & Citations
[1]Grace CR, et al. Solution conformation of non-mammalian tachykinin physalaemin in lipid micelles by nuclear magnetic resonance. Biopolymers. 2011;96 (3) :252-9.|[2]Kobayashi J, Hydrolytic cleavage of pyroglutamyl-peptide bond. V. selective removal of pyroglutamic acid from biologically active pyroglutamylpeptides in high concentrations of aqueous methanesulfonic acid. Chem Pharm Bull (Tokyo) . 2006 Jun;54 (6) :827-31.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NK1R
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-3408R-BF488 100 µL
Phospho-NCOA3 (Thr24) Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Sign In for Pricing
View Details 
