Physalaemin
Product Specifications
UNSPSC Description
Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with high affinity.
Target Antigen
Neurokinin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Physalaemin.html
Solubility
10 mM in H2O
Smiles
OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCCCN)NC([C@H](CC(N)=O)NC([C@H]3N(CCC3)C([C@H](CC(O)=O)NC([C@H](C)NC([C@H]4NC(CC4)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1265.44
References & Citations
[1]Grace CR, et al. Solution conformation of non-mammalian tachykinin physalaemin in lipid micelles by nuclear magnetic resonance. Biopolymers. 2011;96(3):252-9.|[2]Kobayashi J, Hydrolytic cleavage of pyroglutamyl-peptide bond. V. selective removal of pyroglutamic acid from biologically active pyroglutamylpeptides in high concentrations of aqueous methanesulfonic acid. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):827-31.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P0255/Physalaemin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P0255/
Clinical Information
No Development Reported
CAS Number
2507-24-6
Available Sizes
Curated Selection
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