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Corydamine

Corydamine, 3-arylisoquinoline alkaloid, is a potent DNA topoisomerase I/II inhibitor. Corydamine has anti-cancer activity[1].

Product Specifications

CAS Number

49870-84-0

UNSPSC

12352005

Target

Topoisomerase

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/corydamine.html

Solubility

10 mM in DMSO

Smiles

CNCCC1=C(C2=CC3=C(C=N2)C(OCO4)=C4C=C3)C=C(OCO5)C5=C1

Molecular Formula

C20H18N2O4

Molecular Weight

350.37

References & Citations

[1]Xuemei Deng, et al. Design, synthesis and anti-hepatocellular carcinoma activity of 3-arylisoquinoline alkaloids. Eur J Med Chem. 2022 Jan 15;228:113985.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Topo I; Topo II

Frequently Asked Questions

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