TRPM4-IN-2
Product Specifications
Product Name Alternative
NBA
UNSPSC Description
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 μM. TRPM4-IN-2 can be used for researching prostate cancer and colorectal cancer[1][2].
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trpm4-in-2.html
Purity
99.21
Solubility
DMSO : 100 mg/mL (ultrasonic;warming)
Smiles
O=C(O)C1=CC=C(Cl)C=C1NC(COC2=C3C=CC=CC3=CC=C2)=O
Molecular Weight
355.77
References & Citations
[1]Borgström A, et al. Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. J Mol Biol. 2021 Aug 20;433(17):166665.|[2]Stokłosa P, et al. Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers (Basel). 2021 Oct 28;13(21):5400.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128172/TRPM4-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128172/TRPM4-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
667411-04-3
Available Sizes
Curated Selection
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