BMS 310705
BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway[1].
Product Specifications
CAS Number
[280578-49-6]
Product Name Alternative
21-Aminoepothilone B
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-310705.html
Purity
99.10
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@H](C[C@H](OC(C[C@@H](C(C)(C)C([C@H](C)[C@@H](O)[C@@H](C)CCC2)=O)O)=O)/C(C)=C/C3=CSC(CN)=N3)O1
Molecular Formula
C27H42N2O6S
Molecular Weight
522.70
References & Citations
[1]Uyar D, et al. Apoptotic pathways of epothilone BMS 310705. Gynecol Oncol. 2003 Oct;91 (1) :173-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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